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Yes, it is possible. We offer a Magento connector to help you sync data across multiple platforms like eBay. We will be releasing an Amazon connector shortly. Using the nChannel connector for Magento you can quickly and easily integrate and connect Magento to a variety of POS, ERP and accounting systems.
You can read more about our solution here: http://www.nchannel.com/connect-magento-2/
If you have any questions or would like to talk to us directly, feel free to contact us at any time.